WebMay 26, 2010 · Background Prolonged periods of high glucose exposure results in human islet dysfunction in vitro. The underlying mechanisms behind this effect of high glucose are, however, unknown. The polypyrimidine tract binding protein (PTB) is required for stabilization of insulin mRNA and the PTB mRNA 3′-UTR contains binding sites for the … WebLuc Buée is a European scientist (Directeur de Recherche au CNRS - DRCE CNRS), Director of the Lille Neuroscience & Cognition Research Centre and Head of the Inserm laboratory «Alzheimer & Tauopathies» at the University of Lille, France. Located on the Lille hospital campus, his laboratory belongs to the Lille Centre of Excellence in …
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WebOct 30, 2024 · Polypyrimidine tract-binding protein (PTB), also known as heterogeneous nuclear ribonucleoprotein type I (hnRNP I), is a 59.6-kD nuclear protein that binds pre … WebApr 22, 2015 · Abstract and Figures. Polypyrimidine tract-binding protein (PTBP1) is an RNA-binding protein with various molecular functions related to RNA metabolism and a … christine mooneyhan
2adb - Solution structure of Polypyrimidine Tract Binding protein …
WebSolution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA. Summary for 2ADB. Entry DOI: 10.2210/pdb2adb/pdb: Related: 2AD9 2ADC: Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 (2 entities in total) Functional Keywords: WebHuR and polypyrimidine tract binding protein (PTB) have been described as 'global regulators' of RNA alternative splicing, stability, and translation in non-neuronal (including ectodermal) tissues examined to date in diverse species, and REST/NRSF (RE-1 … WebHere we show that genes encoding critical presynaptic proteins are transcribed at a detectable level in both neurons and nonneuronal cells. However, in nonneuronal cells, the splicing of 3′-terminal introns within these genes is repressed by the polypyrimidine tract-binding protein (Ptbp1). christine mooney art