Web为了模拟老化CNS髓鞘形成减少的现象,探究髓鞘形成减少与空间学习记忆能力下降的关系,研究人员构建了Cspg4-CreErt; Olig2 fl/fl;Mapt-mGFP条件敲基因小鼠。在4月龄小鼠模型中,诱导敲除OPC的转录因子Olig2。 WebThe People's Clerk is an office-initiated television show designed to highlight the services and initiatives offered in the Clerk of Superior Court. It airs monthly on Fulton …
Structural basis for CSPG4 as a receptor for TcdB and a ... - Nature
WebDec 14, 2024 · The chondroitin sulfate proteoglycan 4 (CSPG4) gene encodes a transmembrane proteoglycan (PG) constituting the largest and most structurally complex macromolecule of the human surf aceome.Its transcript shows an extensive evolutionary conservation and, due to the elaborated intracellular processing of the translated protein, … WebCSPG4. Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan ( MCSP) or neuron-glial antigen 2 ( NG2 ), is a chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 gene. [5] [6] [7] ind washout
Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in …
WebMar 21, 2024 · CSPG4 (Chondroitin Sulfate Proteoglycan 4) is a Protein Coding gene. Diseases associated with CSPG4 include Melanoma and Demyelinating Disease.Among its related pathways are Chondroitin sulfate/dermatan sulfate metabolism and Glycosaminoglycan metabolism.Gene Ontology (GO) annotations related to this gene … WebJun 26, 2024 · Neuro-glia antigen 2/chondroitin sulfate proteoglycan 4 (NG2/CSPG4, also called MCSP, HMW-MAA, MSK16, MCSPG, MEL-CSPG, or gp240) is a large cell-surface antigen and an unusual cell membrane integral glycoprotein frequently expressed on undifferentiated precursor cells in multiple solid organ cancers, including cancers of the … WebAug 27, 2024 · The NG2-CreERt (The Jackson Laboratory, Catalog # 008538) mouse strain has been described in a previous study (Wang et al., 2024). CreERt expression is under the transcriptional control of the … indwash.co.uk